If you want to lose size on the thighs, exercise the legs doing high repetition. For example, you can jog, do leg lifts while lying on your back, even dancing to music will do. As long as you do this at least 3 times a week for at least 20 minutes. You will begin to notice your energy level go up and your thighs get smaller. However, you also want to reduce your intake of high caloric food and eat lots of fruits and vegetables.
cardio.... only cardio burns fat.
Jogging, cycling, tennis. Anything that primarily uses the muscles on your legs.